AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates
نویسندگان
چکیده
منابع مشابه
AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates.
AMD3100, a bicyclam antagonist of the chemokine receptor CXCR4, has been shown to induce rapid mobilization of CD34(+) hematopoietic cells in mice, dogs, and humans, offering an alternative to G-CSF mobilization of peripheral-blood hematopoietic stem cells. In this study, AMD3100-mobilized CD34(+) cells were phenotypically analyzed, marked with Neo(R)-containing retroviral vectors, and subseque...
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ژورنال
عنوان ژورنال: Blood
سال: 2006
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2005-09-3592